GHK-Cu
Copper tripeptide-1 · prezatide copper acetate
The copper(II) complex of glycyl-L-histidyl-L-lysine, studied as a copper carrier and modulator of extracellular matrix remodelling.
GHK-Cu is the 1:1 copper(II) complex of the tripeptide GHK, carrying the INN prezatide copper acetate. It is widely used as a cosmetic ingredient and has been studied in wound-healing and matrix-remodelling models.
Supplied as a lyophilised blue powder — the colour is from the copper complex and is expected. Not approved as a therapeutic drug product.
Specification
| CAS number | 89030-95-5 |
|---|---|
| Molecular formula | C14H23CuN6O4+ |
| Molecular weight | 402.92 g/mol |
| Purity | ≥99% (HPLC) |
| Sequence | Gly-His-Lys (GHK), copper(II) complex |
| Appearance | Lyophilised white powder |
| Storage | Store at -20°C, protect from light |
Batch records & certificates
Every lot we hold of this compound, across all warehouses. The certificate is tied to that lot number — not a generic sample document.
| Lot | Warehouse | Purity | Tested | Laboratory | Documents |
|---|---|---|---|---|---|
| GH25-0081 | India | 99.5% | 8 Jul 2026 | Colmaric Analyticals | COA pending |
| GH25-0077 | United Kingdom | 99.6% | 11 Jun 2026 | Colmaric Analyticals | COA pending |
Published research
Full research profilePreclinical evidence only
GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration
Reviews the proposed roles of GHK in skin remodelling, copper transport and gene expression modulation.
Expression and activation of matrix metalloproteinases in wounds: modulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+
In a rat wound model, GHK-Cu altered MMP and TIMP expression, indicating a role in controlled matrix remodelling.
The effect of topical tripeptide-copper complex on healing of ischemic open wounds
Topical application accelerated closure of ischaemic open wounds relative to control in an animal model.